Internal Medicine Glossary

A

  • Ankle-Brachial Index (ABI)

    • Definition: Ratio of systolic blood pressure at the ankle to the systolic blood pressure at the brachial artery.

    • Purpose: Assesses for peripheral arterial disease (PAD).

    • Interpretation:

      • Normal: 1.0 – 1.4

      • Borderline: 0.91 – 0.99

      • PAD: ≤ 0.90

      • Severe ischemia: < 0.4

  • Arterial Pulses

    • Sites to palpate: Radial, brachial, carotid, femoral, popliteal, posterior tibial, dorsalis pedis.

    • Assessment: Rate, rhythm, volume, symmetry, and character (e.g., bounding, weak, thready).

    • Clinical clues: Absent or diminished pulses suggest arterial occlusion or stenosis.


B

  • Bruits

    • Definition: Audible vascular sounds (murmurs) heard over arteries, indicating turbulent blood flow.

    • Common sites: Carotid artery, abdominal aorta, femoral artery.

    • Clinical significance: Suggests stenosis or aneurysm.

  • Buerger’s Test

    • Description: Elevate legs to 45 degrees for 1-2 minutes, observe for pallor; then lower legs and note time for color to return.

    • Purpose: Evaluates arterial insufficiency.

    • Positive test: Delayed color return indicates ischemia.


C

  • Capillary Refill Time (CRT)

    • Method: Press on nail bed or skin until blanching, release, and measure time for color to return.

    • Normal: < 2 seconds

    • Prolonged CRT: Indicates poor peripheral perfusion or shock.

  • Claudication

    • Definition: Cramping leg pain induced by exercise due to ischemia from arterial insufficiency.

    • History relevance: Helps localize level of arterial obstruction.


D

  • Dermatological Signs

    • Assessment of skin: Color, temperature, texture, hair distribution, trophic changes (thin, shiny skin), ulcers.

    • Significance: Arterial insufficiency may cause pallor, hair loss, cool skin; venous disease often causes pigmentation, eczema.

  • Deep Vein Thrombosis (DVT) Signs

    • Clinical features: Swelling, warmth, redness, tenderness of the limb.

    • Examination: Measure calf circumference, Homans’ sign (pain on dorsiflexion).


E

  • Edema

    • Definition: Abnormal accumulation of fluid in interstitial tissues.

    • Types: Pitting (press skin leaves indentation) vs non-pitting.

    • Causes: Venous insufficiency, lymphatic obstruction, heart failure, renal disease.

  • Elevation Pallor

    • Definition: Pale discoloration of limbs when elevated, indicating arterial insufficiency.


F

  • Femoral Pulse

    • Location: Below the inguinal ligament, midway between the anterior superior iliac spine and pubic symphysis.

    • Clinical: Palpation important in assessing arterial flow to the lower limb.


H

  • Homans’ Sign

    • Test: Pain in the calf on passive dorsiflexion of the foot.

    • Clinical utility: Historically used for DVT but has low sensitivity and specificity.


L

  • Lymphadenopathy

    • Definition: Enlargement of lymph nodes.

    • Peripheral vascular exam: Palpate inguinal nodes for infection, malignancy, or inflammation.

  • Lymphoedema

    • Description: Chronic swelling caused by lymphatic obstruction.

    • Characteristics: Non-pitting edema, skin thickening, and fibrosis.


M

  • Medial Malleolus Ulcers

    • Description: Typical location of venous ulcers caused by chronic venous insufficiency.

    • Features: Irregular margins, shallow base, associated pigmentation.


P

  • Peripheral Cyanosis

    • Definition: Bluish discoloration of extremities due to reduced oxygen delivery.

    • Causes: Vasoconstriction, arterial obstruction, or venous congestion.

  • Peripheral Pulses

    • See arterial pulses.

  • Phlebitis

    • Definition: Inflammation of a vein, often superficial, causing pain, redness, and swelling.

  • Popliteal Pulse

    • Location: Behind the knee in the popliteal fossa.

    • Clinical relevance: Difficult to palpate; absence suggests arterial occlusion.


R

  • Raynaud’s Phenomenon

    • Description: Episodic vasospasm of the small arteries of the fingers and toes causing color changes (white → blue → red).

    • History: Triggered by cold or stress; associated with pain and numbness.


S

  • Skin Temperature

    • Assessment: Compare limb temperatures bilaterally.

    • Cool limb: Suggests arterial insufficiency.

    • Warm limb: Suggests inflammation or infection.

  • Swelling

    • See edema.


T

  • Trendelenburg Test

    • Purpose: Assess venous valve competence in the legs.

    • Procedure: Leg elevated, tourniquet applied to thigh, patient stands, observe venous filling.

    • Abnormal: Rapid filling indicates incompetent valves.

  • Trophic Changes

    • Definition: Changes in skin and nails due to chronic ischemia or venous disease.

    • Examples: Hair loss, thickened nails, shiny skin.


V

  • Venous Return

    • Observation: Examine for varicosities, venous ulcers, pigmentation.

    • Tests: Trendelenburg test, manual compression test for varicose veins.

  • Varicose Veins

    • Definition: Dilated, tortuous superficial veins caused by valve incompetence.

    • Signs: Visible dilated veins, aching, heaviness.

  • Venous Ulcers

    • Characteristics: Located above the medial malleolus, irregular edges, associated with stasis pigmentation and edema.


General Examination Tips

  • Examine patient both standing and supine to assess arterial and venous systems accurately.

  • Use inspection, palpation, and auscultation systematically.

  • Always compare both limbs for symmetry in pulses, temperature, and skin changes.

  • Consider systemic signs (e.g., clubbing, pallor, cyanosis) during the exam.

  • Document findings clearly with attention to location, size, character, and associated symptoms.

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