Internal Medicine Glossary

A

  • Ankle Clonus

    • Definition: Involuntary, rhythmic muscle contractions and relaxations in response to sudden dorsiflexion of the foot.

    • Clinical significance: Indicates upper motor neuron (UMN) lesion (e.g., stroke, spinal cord injury).

    • Exam tip: Test by briskly dorsiflexing the ankle and holding; observe for repetitive beats.

  • Atrophy

    • Definition: Loss of muscle bulk due to denervation or disuse.

    • Significance: Suggests lower motor neuron (LMN) lesions, peripheral neuropathy, or chronic disuse.

    • Exam tip: Compare muscle bulk bilaterally, especially in calf and thigh.


B

  • Babinski Sign

    • Definition: Upgoing plantar reflex where the big toe dorsiflexes and other toes fan out when the lateral sole is stroked.

    • Significance: Indicative of UMN lesion affecting corticospinal tract.

    • Exam tip: Use a blunt object to stroke the sole firmly from heel to toes.

  • Balance

    • Definition: Ability to maintain posture and equilibrium.

    • Exam tip: Assess using Romberg test (standing feet together, eyes closed) and gait assessment.


C

  • Clonus

    • See Ankle Clonus.

  • Coordination

    • Definition: Smooth, accurate, and controlled muscle movements.

    • Exam: Heel-to-shin test for lower limb coordination to assess cerebellar function.


D

  • Deep Tendon Reflexes (DTRs)

    • Common lower limb reflexes:

      • Patellar reflex (L3-L4): Knee jerk elicited by tapping patellar tendon.

      • Achilles reflex (S1): Ankle jerk elicited by tapping Achilles tendon.

    • Clinical relevance:

      • Increased reflexes → UMN lesion.

      • Reduced/absent reflexes → LMN lesion or peripheral neuropathy.

  • Dermatomes

    • Definition: Areas of skin innervated by sensory fibers of a single spinal nerve root.

    • Exam: Test light touch, pinprick, and temperature along L2-S2 dermatomes to localize sensory deficits.


F

  • Foot Drop

    • Definition: Inability to dorsiflex the foot due to weakness of the anterior tibialis muscle.

    • Causes: Peroneal nerve palsy, L5 radiculopathy, stroke.

    • Exam tip: Assess dorsiflexion strength and gait (steppage gait).


G

  • Gait

    • Types: Normal, ataxic, spastic, steppage, waddling.

    • Exam: Observe walking normally, on heels and toes, and tandem gait (heel-to-toe).

    • Significance: Different gait patterns indicate different neurological or muscular pathologies.


H

  • Hypotonia

    • Definition: Decreased muscle tone resulting in floppy limbs.

    • Significance: Suggests LMN lesion, cerebellar disease, or acute peripheral neuropathy.


I

  • Inversion & Eversion of Foot

    • Definition: Movements controlled by different nerve roots and peripheral nerves.

    • Clinical relevance: Weakness may localize lesions to L4-L5 (inversion) or L5-S1 (eversion).


M

  • Muscle Power

    • Assessment: Graded 0 to 5 (0 = no movement; 5 = normal strength).

    • Key muscle groups:

      • Hip flexors (L2-L3),

      • Knee extensors (L3-L4),

      • Ankle dorsiflexors (L4-L5),

      • Plantar flexors (S1).

    • Exam tip: Compare bilaterally and test against resistance.

  • Muscle Tone

    • Definition: Resistance to passive movement.

    • UMN lesion: Increased tone (spasticity).

    • LMN lesion: Decreased tone (flaccidity).


P

  • Plantar Reflex

    • See Babinski Sign.

  • Proprioception

    • Definition: Awareness of limb position in space.

    • Exam: Move patient’s big toe up or down with eyes closed and ask direction.

    • Significance: Loss suggests dorsal column dysfunction.


R

  • Reflexes

    • See Deep Tendon Reflexes.

  • Romberg Test

    • Definition: Assessment of proprioception and balance.

    • Exam: Patient stands with feet together and eyes closed; loss of balance indicates proprioceptive or vestibular dysfunction.


S

  • Sensory Testing

    • Modalities: Light touch, pain (pinprick), temperature, vibration, and proprioception.

    • Exam tip: Test systematically on lower limbs to identify pattern of sensory loss (e.g., dermatomal, stocking-glove).

  • Spasticity

    • Definition: Velocity-dependent increase in muscle tone.

    • Significance: Classic UMN sign.

  • Straight Leg Raise (SLR) Test

    • Purpose: Assess for lumbar radiculopathy, especially L5-S1 nerve roots.

    • Positive test: Reproduction of sciatic pain between 30-70 degrees of leg elevation.


T

  • Tone

    • See Muscle Tone.

  • Tendon Reflexes

    • See Deep Tendon Reflexes.


V

  • Vibration Sense

    • Exam: Use a 128 Hz tuning fork on bony prominences (e.g., medial malleolus).

    • Significance: Loss seen in peripheral neuropathy, dorsal column disease.


Key Clinical Pearls

  • UMN lesions → increased tone, hyperreflexia, positive Babinski, clonus, spasticity.

  • LMN lesions → decreased tone, hyporeflexia, muscle atrophy, fasciculations.

  • Sensory deficits help localize lesions: dermatomal patterns suggest nerve root pathology; stocking-glove pattern suggests peripheral neuropathy.

  • Gait assessment provides valuable clues for lesion localization and severity.

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