Internal Medicine Glossary

A

  • Anatomical Snuffbox

    • Definition: Triangular depression on the lateral wrist visible when the thumb is extended.

    • Clinical significance: Tenderness here suggests scaphoid fracture or De Quervain’s tenosynovitis.

  • Arthritis

    • Definition: Inflammation of one or more joints causing pain, swelling, stiffness.

    • Types relevant to the hand: Rheumatoid arthritis (RA), osteoarthritis (OA), psoriatic arthritis.


B

  • Boutonnière Deformity

    • Definition: Flexion of the proximal interphalangeal (PIP) joint and hyperextension of the distal interphalangeal (DIP) joint.

    • Cause: Rupture of the central slip of the extensor tendon, commonly in RA or trauma.

  • Bouchard’s Nodes

    • Definition: Bony enlargements at the PIP joints.

    • Associated with: Osteoarthritis.

  • Bilateral Symmetry

    • Importance: Symmetrical joint involvement favors inflammatory arthritis like RA over degenerative causes.


C

  • Carpal Tunnel Syndrome (CTS)

    • Definition: Median nerve compression at the wrist causing pain, numbness, and tingling in the thumb, index, middle, and radial half of the ring finger.

    • Examination signs: Positive Tinel’s sign and Phalen’s test.

  • Crepitus

    • Definition: Grating or crackling sensation felt on joint movement, indicating roughened articular surfaces (e.g., in OA).


D

  • DIP Joint

    • Definition: Distal interphalangeal joint (closest to the fingertip).

    • Commonly involved in: Osteoarthritis and psoriatic arthritis.

  • De Quervain’s Tenosynovitis

    • Definition: Inflammation of the tendons on the radial side of the wrist.

    • Test: Positive Finkelstein’s test (pain on ulnar deviation of the wrist with thumb flexed).


E

  • Erosion

    • Definition: Bone loss seen on X-ray at joint margins, characteristic of inflammatory arthritis like RA.

  • Effusion

    • Definition: Accumulation of excess synovial fluid within a joint.

    • Detectable by: Swelling, palpable fluid wave, sometimes fluctuation.


F

  • Flexion Contracture

    • Definition: Inability to fully extend a finger due to shortening of tendons or ligaments.

    • Common cause: Dupuytren’s contracture.

  • Finkelstein’s Test

    • Purpose: Diagnose De Quervain’s tenosynovitis.

    • Procedure: Patient grasps thumb, ulnar deviation of wrist causes pain if positive.


G

  • Ganglion Cyst

    • Definition: Noncancerous fluid-filled cyst near joints or tendons, commonly on the dorsum of the wrist.

    • Clinical note: May fluctuate in size; usually painless but can cause discomfort.


H

  • Heberden’s Nodes

    • Definition: Bony enlargements at the DIP joints.

    • Significance: Classic feature of osteoarthritis.

  • Hypothenar Eminence

    • Definition: Muscular bulge on the ulnar side of the palm.

    • Atrophy here can indicate ulnar nerve pathology.


I

  • Interphalangeal Joints

    • Definition: Joints between the phalanges; include PIP and DIP joints.

  • Inflammation Signs

    • Include: Redness, warmth, swelling, tenderness, and loss of function.


J

  • Joint Line Tenderness

    • Definition: Pain on palpation along the joint margins.

    • Indicates: Synovitis, arthritis, or joint pathology.


L

  • Lumbrical Muscles

    • Function: Flex the metacarpophalangeal (MCP) joints and extend the interphalangeal joints.

    • Weakness may cause deformities in rheumatoid arthritis.


M

  • Metacarpophalangeal (MCP) Joint

    • Definition: Joint between the metacarpal bones and proximal phalanges.

    • Commonly affected in rheumatoid arthritis.

  • Muscle Wasting

    • Significance: Suggests chronic nerve compression or disuse atrophy.


N

  • Nodules

    • Rheumatoid Nodules: Firm, non-tender subcutaneous lumps seen in RA, often over extensor surfaces.


O

  • Osteoarthritis (OA)

    • Definition: Degenerative joint disease characterized by cartilage loss and bony proliferation.

    • Hand signs: Heberden’s and Bouchard’s nodes, joint stiffness, and crepitus.


P

  • Phalen’s Test

    • Purpose: Diagnoses carpal tunnel syndrome.

    • Procedure: Patient flexes wrists maximally and holds position for 60 seconds; tingling/numbness suggests median nerve compression.

  • Power Grip

    • Definition: Gripping object with palm and fingers.

    • Assessment: Tests overall hand strength.

  • PIP Joint

    • Definition: Proximal interphalangeal joint (middle joint of fingers).


R

  • Rheumatoid Arthritis (RA)

    • Features: Symmetrical joint swelling, morning stiffness >1 hour, involvement of MCP and PIP joints.

    • Deformities: Swan-neck, Boutonnière, ulnar deviation.

  • Range of Motion (ROM)

    • Assessment: Active and passive joint movements to detect stiffness or contracture.


S

  • Swan-neck Deformity

    • Definition: Hyperextension of the PIP joint and flexion of the DIP joint.

    • Causes: Rheumatoid arthritis, trauma.

  • Synovitis

    • Definition: Inflammation of the synovial membrane, causing swelling and tenderness.

  • Swelling

    • Localized or diffuse, indicates joint or soft tissue pathology.


T

  • Trigger Finger (Stenosing Tenosynovitis)

    • Definition: Finger stuck in flexed position that suddenly releases with a snap.

    • Cause: Thickening or inflammation of the flexor tendon sheath.

  • Tenderness

    • Assessment: Palpate joint margins, tendon insertions, and soft tissues for pain.


W

  • Wrist Drop

    • Definition: Inability to extend the wrist and fingers.

    • Cause: Radial nerve palsy.


Examination Maneuvers & Tests

Test Purpose Procedure Positive Sign
Tinel’s Sign Carpal tunnel syndrome Tap over median nerve at wrist Tingling in median nerve distribution
Phalen’s Test Carpal tunnel syndrome Hold wrist in flexion 60 seconds Numbness/tingling in median nerve area
Finkelstein’s Test De Quervain’s tenosynovitis Ulnar deviation with thumb flexed Pain over radial styloid
Grip Strength Assess overall hand muscle power Patient squeezes examiner’s fingers Weakness suggests neuropathy or arthritis
Joint Line Palpation Detect joint inflammation Palpate joint margins Tenderness or swelling

Clinical Pearls

  • Always compare both hands for symmetry of findings.

  • Look for subtle deformities and nodules—early RA signs can be missed.

  • Assess functional impact on daily activities like buttoning, gripping, and writing.

  • Check for sensory changes to evaluate for nerve compression syndromes.

  • Remember that morning stiffness >1 hour strongly suggests inflammatory arthritis.

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