
About Course
The Internal Medicine Mastery Course offers an in-depth, clinically integrated exploration of adult medicine. Designed by medical professionals for healthcare learners, this course equips students and practitioners with critical knowledge, diagnostic skills, and management strategies essential for managing complex multisystem diseases.
This course emphasizes evidence-based medicine, high-yield clinical concepts, and real-world application through lectures, interactive case vignettes, mind maps, and integrated tables. Covering all major systems—including cardiovascular, respiratory, renal, endocrine, gastrointestinal, and more—it serves as a foundational pillar for medical students, interns, clinical officers, and practicing physicians aiming to sharpen their diagnostic acumen and patient care.
What Will You Learn?
- By the end of this course, you will be able to:
- Understand the pathophysiology and presentation of common and critical internal medicine conditions.
- Interpret diagnostic tests and imaging relevant to internal medicine.
- Develop comprehensive, evidence-based management plans.
- Differentiate between similar disease entities using clinical reasoning.
- Apply internal medicine principles to real-world clinical scenarios.
- Prepare confidently for medical board/licensing exams with high-yield content and quizzes.
Course Content
History and Examination
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Taking a-History
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Symptoms
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Physical Examination
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The Cardiovascular System: History
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Pulses
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The Jugular Venous Pressure (JVP)
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The Heart Sounds
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Cardiac Murmurs
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The Respiratory System: History
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The Gastrointestinal System: History
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Examination of the Abdomen
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The Neurological System: History
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Neurological Examination of the Upper Limbs
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Neurological Examination of the Lower Limbs
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Cranial Nerve Examination
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Cranial Nerve Lesions of the Eye
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Musculoskeletal Hand Examination
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The Peripheral Vascular System: Examination
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Arterial
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Venous
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The Genitourinary System: History
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The Breast: History
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The Thyroid: Examination
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Speech and Higher Mental Function
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Movement Disorders
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Psychiatry Assessment
Cardiovascular Medicine
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Cardiovascular Health
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Cardiovascular Symptoms
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ECG- A Methodical Approach
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ECG- Abnormalities
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Cardiac Imaging
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Echocardiography
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Cardiac Catheterization
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Cardiovascular Drugs
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Angina Pectoris
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Acute Coronary Syndromes (ACS)
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Management of ACS
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Complications of MI
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Arrhythmias- Overview
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Continuous ECG Monitoring
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Narrow Complex Tachycardia
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Broad Complex Tachycardia
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Atrial Fibrillation (AF) and Flutter
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Pacemakers
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Heart Failure- Basic Concepts
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Heart Failure- Management
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Hypertension
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Hypertension- Management
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Rheumatic Fever (RF)
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Mitral Valve Disease
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Aortic Valve Disease
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Right Heart Valve Disease
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The Heart in Various, Mostly Rare, Systemic Diseases
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Infective Endocarditis (IE)
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Diseases of Heart Muscle
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Pericardial Diseases
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Adult Congenital Heart Disease (ACHD)
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Driving and the Heart
Chest Medicine
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Respiratory Health
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Bedside Tests in Chest Medicine
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Pneumonia
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Specific Pneumonias
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Complications of Pneumonia
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Bronchiectasis
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Cystic Fibrosis (CF)
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Lung Tumors
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Lung Tumors: Staging and Treatment
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Fungi and the Lung
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Asthma
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Management of Chronic Asthma
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Chronic Obstructive Pulmonary Disease (COPD)
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Acute Respiratory Distress Syndrome (ARDS)
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Respiratory Failure
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Pulmonary Embolism (PE)
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Pneumothorax
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Pleural Effusion
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Obstructive Sleep Apnoea Syndrome
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Cor Pulmonale
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Sarcoidosis
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Interstitial Lung Disease (ILD)
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Extrinsic Allergic Alveolitis (EAA)
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Idiopathic Pulmonary Fibrosis (IPF)
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Industrial Dust Diseases
Endocrinology
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The Essence of Endocrinology
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Endocrine Physiology
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Classification and Diagnosis
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Treating Diabetes Mellitus
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Complications of Established Diabetes
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Diabetic Neuropathy and Diabetic Foot Care
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Hypoglycaemia
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Insulinoma
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Thyroid Function Tests (TFTs)
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Thyrotoxicosis
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Hypothyroidism (Myxoedema)
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Parathyroid Hormone and Hyperparathyroidism
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Hypoparathyroidism
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Adrenal Cortex and Cushing’s Syndrome
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Addisons Disease (Adrenal Insufficiency)
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Hyperaldosteronism
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Phaechromocytoma
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Hirsutism, Virilism, Gynaecomastia and Impotence
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Hypopituitarism
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Pituitary Tumors
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Hyperprolactinaemia
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Acromegaly
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Diabetes Insipidus (DI)
Gastroenterology
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Healthy, Enjoyable Eating
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The Mouth
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Endoscopy and Biopsy
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Dysphagia
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Nausea and Vomiting
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Dyspepsia and Peptic Ulcer Disease
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Gastro-oesophageal Reflux Disease (GORD)
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Upper Gastrointestinal Bleeding
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Diarrhoea
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Constipation
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Ulcerative Colitis (UC)
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Crohn’s Disease
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Gastrointestinal Malabsorption
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Coeliac Disease
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Irritable Bowel Syndrome (IBS)
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Nutritional Disorders
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Chronic Pancreatitis
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Carcinoma of the Pancreas
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Carcinoid Tumors
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Jaundice
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Liver Failure
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Cirrhosis
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Viral Hepatitis
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Alcoholism
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Primary Biliary Cholangitis (PBC)
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Primary Sclerosing Cholangitis (PSC)
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Autoimmune Hepatitis (AIH)
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Non-alcoholic Fatty Liver Disease (NAFLD)
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Wilsons Disease/hepatolenticular Degeneration
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Liver Tumors
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Hereditary Haemochromatosis (HH)
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Antitrypsin (A1AT) Deficiency
Renal Medicine
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Urine
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Urinary Tract Infection (UTI)
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Acute Kidney Injury (AKI)
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Management
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Chronic Kidney Disease (CKD)
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Renal Replacement Therapy (RPT)
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Dialysis and Filtration
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Transplantation
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Glomerulonephritis
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Nephrotic Syndrome
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Renal Manifestations of Systemic Disease
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The Renal Tubule: Disorders and Diuretics
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Tubulointerstitial Nephropathy and Nephrotoxins
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Inherited Kidney Disease
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Nephritic Syndrome
Haematology
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Anaemia
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Iron-deficiency Anaemia
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Anaemia of Chronic Disease
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Sideroblastic Anaemia
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The Peripheral Blood Film
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The Differential White Cell Count
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Macrocytic Anaemia
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B12 Deficiency and Pernicious Anaemia
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An approach to Haemolytic Anaemia
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Sickle-Cell Anaemia
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Thalassaemia
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Bleeding Disorders
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Coagulation Pathways
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An Approach to Bleeding
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Blood Transfusion and Blood Products
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Anticoagulants
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Leukaemia
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Acute Lymphoblastic Leukaemia
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Acute Myeloid Leukaemia
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Chronic Myeloid Leukaemia
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Chronic Lymphocytic Leukaemia
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Hodgkins Lymphoma
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Non-Hodgkins Lymphoma
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Pancytopenia and Bone Marrow Failure
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Myeloproliferative Disorders
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Myeloma
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Paraproteinaemia
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Amyloidosis
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Erythrocyte Sedimentation Rate (ESR)
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Plasma Viscosity (PV)
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Hyperviscosity Syndrome
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The Spleen and Splenectomy
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Thrombophilia
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Immunosuppressive Drugs
Infectious Diseases
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What is Life?
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Infectious Disease: an Overview
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Bacterial Disease: an Overview
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Antibiotics
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Antibiotics: Summary Tablets
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Gram-positive Bacteria
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Gram-Negative Bacteria
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Tuberculosis (TB): Presentation
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Tuberculosis (TB): Diagnosis and Treatment
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Influenza
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Human Immunodeficiency Virus (HIV): Diagnosis
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Complications of HIV Infection
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HIV Antiretroviral Therapy (ART)
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Herpes Viruses
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Other Viruses
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Immunization
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Fungi
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Healthcare-associated (Nosocomial) Infection
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Sexually Transmitted Infection (STI)
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Enteric Fever
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Malaria: Diagnosis
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Malaria: Treatment
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Mosquito-borne Disease
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Vector-borne Disease
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Zoonoses
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Viral Haemorrhagic Fever (VHF)
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Gastroenteritis: an Overview
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Gastroenteritis: Specific Infections
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Gastrointestinal Parasites
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Schistosomiasis and Liver Disease
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Neurological Disease
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Eye Disease
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Skin Disease
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Pyrexia of Unknown Origin
Neurology
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Where is the Lesion?
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Drugs and the Nervous System
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Cerebral Blood Supply
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Testing Peripheral Nerves
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Dermatomes and Peripheral Nerves
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Headache
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Migraine
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Blackouts
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Vertigo and Dizziness
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Hearing Loss and Tinnitus
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Acute Bilateral Leg Weakness
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Abnormal Involuntary Movements (Dyskinesia)
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Stroke: Clinical Features and Acute Management, Investigation and Prevention
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Re-enablement After Stroke
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Transient Ischaemic Attack (TIA)
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Subarachnoid Haemorrhage (SAH)
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Intracranial Venous Thrombosis (IVT)
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Subdural Haematoma
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Extradural (Epidural) Haematoma
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Delirium (Acute Confusional State)
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Dementia
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Alzheimer’s Disease (AD)
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Epilepsy: Diagnosis
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Epilepsy: Management
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Parkinsonism
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Multiple Sclerosis (MS)
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Space-occupying Lesions (SOL)
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Idiopathic Intracranial Hypertension
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Bell’s Palsy
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Mononeuropathies
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Polyneuropathies
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Autonomic Neuropathy
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Motor Neuron Disease (MND)
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Bulbar Palsy
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Cervical Spondylosis
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Myopathy
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Myasthenia Gravis (MG)
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Lambert-Eaton Myasthenic Syndrome (LEMS)
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Neurofibromatosis
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Syringomyelia
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Retroviruses and Neurology
Oncology and Palliative Care
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Looking After People With Cancer
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The Genetics of Cancer
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Cancer Diagnosis
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Cancer Treatment: Medicine and Surgery
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Cancer Treatment: Radiotherapy
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Interventional Oncology
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Oncology Emergencies
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Paraneoplastic Syndromes
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Tumour Markers
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Palliative Care
Rheumatology
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The Rheumatological History
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Assessing The Locomotor System
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Rheumatological Investigations
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Back Pain
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Osteoarthritis
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Septic Arthritis
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Rheumatoid Arthritis
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Crystal Arthropathies: Gout & CPPD Arthropathy
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Spondyloarthritides: Ankylosing Spondylitis, Enteropathic, Psoriatic & Reactive arthritis
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Systemic Sclerosis
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Mixed Connective Tissue Disease
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Relapsing Polychondritis
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Polymyositis & Dermatomyositis
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Systemic Lupus Erythematosus
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Gaint Cell Arteritis
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Polyarteritis Nodosa
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Microscopic Polyangiitis
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Polymyalgia Rheumatica
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Fibromyalgia
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Systemic Disease with Ocular Manifestations
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Systemic Disease with Dermatological Manifestations
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Acute SLE
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Acute Systemic Vasculitis
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Acute Cord Compression
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Methotrexate Induced Pneumonitis
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Neutropenic Sepsis
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Scleroderma: Pulmonary Hypertensive or Renal Crisis
Clinical Chemistry
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The Essence of Labratory Medicine
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Biochemistry: Some Major Disease Patterns
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Lab Results: Act Now
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Fluid Balance and IV Fluid Therapy
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Electrolyte Physiology and the Kidney
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Acid-Base Balance
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Hyper and Hyponatraemia
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Syndrome of Inappropriate ADH Secretion
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Hyper and Hypokalaemia
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Calcium and Phosphate Physiology
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Hypercalcaemia
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Hypocalcaemia
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Phosphate, Magnesium, Zinc & Selenium
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Urate and the Kidney
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Metabolic bone diseases
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Plasma Proteins
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Urinary Proteins
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Plasma Enzymes
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Hyperlipidaemia
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The Porphyrias
Practical Procedures
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Nasogastric Tubes
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Placing lV Cannulae
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Cut Down on to a Vein
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Catheterizing Bladders
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Diagnostic Aspiration of a Pleural Effusion
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Abdominal Paracentesis
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Inserting a Chest Drain
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Relieving a Tension Pneumothorax
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Lumbar Puncture (LP)
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Cardioversion/Defibrillation
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Arterial Blood Gas Sampling
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Emergency Airway Management
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Central Venous Cannulation
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Internal Jugular Catheterization
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Inserting a Temporary Cardiac Pacemaker
Emergencies
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Headache
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Breathlessness
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Chest Pain
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Coma
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The Glasgow Coma Scale (GCS)
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Shock
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Sepsis
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Anaphylactic Shock
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Acute Coronary Syndrome -with ST Elevation
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Acute Coronary Syndrome -without ST Elevation
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Severe Pulmonary Oedema
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Cardiogenic Shock
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Broad Complex Tachycardia
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Narrow Complex Tachycardia
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Bradycardia
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Acute Severe Asthma
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Acute Exacerbations of COPD
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Pneumothorax
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Tension Pneumothorax
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Pneumonia
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Pulmonary Embolism (PE)
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Acute Upper GI Bleeding
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Meningitis
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Encephalitis
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Cerebral Abscess
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Status Epilepticus
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Head Injury
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Raised Intracranial Pressure (ICP)
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Diabetic Ketoacidosis (DKA)
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Other Diabetic Emergencies
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Thyroid Emergencies
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Addisonian Crisis
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Hypopituitary Coma
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Phaeochromocytoma Emergencies
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Acute Poisoning
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Some Specific Poisons and their Antidotes
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Paracetamol poisoning
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Salicylate Poisoning
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Burns
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Hypothermia