Internal Medicine Glossary

A

  • Auscultation of Thyroid

    • Definition: Listening over the thyroid gland with a stethoscope for vascular sounds (bruits).

    • Clinical significance: Presence of a bruit suggests increased blood flow, commonly seen in hyperthyroidism (e.g., Graves’ disease).

  • Asymmetry

    • Observation: Unequal size or shape of thyroid lobes.

    • Significance: May indicate nodules, cysts, or malignancy.


B

  • Brisk Reflexes

    • Definition: Hyperactive deep tendon reflexes often seen in hyperthyroidism.

    • Examination: Test the biceps, triceps, or ankle reflexes.


C

  • Consistency (of thyroid gland)

    • Normal: Soft and smooth.

    • Firm or hard: Suggests fibrosis or malignancy.

    • Tenderness: Can indicate thyroiditis.

  • Cold Nodule

    • Definition: On thyroid scans, areas that do not uptake isotope.

    • Clinical note: Usually non-functioning; higher risk of malignancy, but this is from imaging, important to suspect on examination if firm nodule present.

  • Crackles (Chest Exam relevance)

    • Not directly thyroid exam but assess for heart failure signs, sometimes seen in severe hypothyroidism.


D

  • Diffuse Enlargement

    • Description: Uniform thyroid swelling without distinct nodules.

    • Common causes: Graves’ disease, Hashimoto’s thyroiditis, iodine deficiency.


E

  • Erythema and Warmth over Thyroid

    • Indicates: Acute thyroiditis or inflammation.


F

  • Firmness

    • Definition: Feeling of the gland on palpation.

    • Implication: Firm or hard glands suggest malignancy or fibrosis.


G

  • Goitre

    • Definition: Enlargement of the thyroid gland, visible or palpable.

    • Types: Diffuse, multinodular, solitary nodule.

    • Assessment: Size, shape, consistency, mobility.


H

  • Hard Nodule

    • Concern: May indicate malignancy.

    • Examination: Palpate nodules for size, mobility, tenderness.

  • Hypothyroid Signs on Exam

    • Dry skin, coarse hair, bradycardia, delayed relaxation phase of reflexes.


I

  • Inspiratory Retraction

    • Definition: Visible inward movement of the suprasternal notch or lower neck on inspiration.

    • Significance: Large goitre causing airway obstruction.


L

  • Lymphadenopathy

    • Definition: Enlarged cervical lymph nodes near the thyroid.

    • Significance: Suggests malignancy or infection.


M

  • Mobility of Thyroid Gland

    • Normal: Moves upward on swallowing due to attachment to the trachea.

    • Fixation: Suggests invasive malignancy.

  • Multinodular Goitre

    • Definition: Thyroid with multiple nodules; may be large and irregular.


N

  • Nodules

    • Palpable lumps within the thyroid.

    • Features to note: Size, number, consistency, tenderness, mobility, associated lymphadenopathy.

    • Clinical importance: Some nodules may be malignant; others benign or cystic.


P

  • Pemberton’s Sign

    • Test: Patient raises arms above the head for 1-2 minutes.

    • Positive sign: Facial flushing, cyanosis, or respiratory distress due to compression of thoracic inlet by a large goitre.

  • Pulse (Thyroid exam relevance)

    • Observation: Tachycardia may be present in hyperthyroidism.

  • Periorbital Edema

    • Seen in: Hypothyroidism (myxedema).


R

  • Retrosternal Extension

    • Definition: Goitre extends into the thoracic inlet, not easily palpable but causing compressive symptoms.

    • Clues: Dysphagia, dyspnea, hoarseness.


S

  • Size (of thyroid)

    • Assessment: Measure by palpation; use inspection for visible enlargement.

    • Normal: Not visible or only a slight prominence on swallowing.

  • Skin Changes

    • Thin, warm, moist skin: Hyperthyroidism.

    • Dry, coarse skin: Hypothyroidism.

  • Stridor

    • Audible high-pitched sound on inspiration.

    • Significance: Airway obstruction by large thyroid mass.


T

  • Tenderness

    • Pain on palpation.

    • Indicates: Thyroiditis or hemorrhage into cyst/nodule.

  • Thyroid Bruit

    • Heard on auscultation.

    • Indicates: Increased vascularity (e.g., Graves’ disease).

  • Thyroid Stimulating Hormone (TSH) Testing

    • Lab test: Not part of physical exam but essential to correlate clinical findings.


V

  • Voice Changes / Hoarseness

    • Possible cause: Recurrent laryngeal nerve involvement from large goitre or malignancy.


W

  • Warmth of Thyroid

    • Increased temperature over gland indicates inflammation or hyperactivity.


Examination Technique Overview

  • Inspection: Look for swelling, scars, skin changes, visible pulsations, or asymmetry.

  • Palpation: Use both hands to palpate from behind; feel for size, shape, nodules, tenderness, consistency, and mobility on swallowing.

  • Auscultation: Listen over the thyroid for bruits with the diaphragm of the stethoscope.

  • Special tests: Pemberton’s sign to detect thoracic inlet obstruction.

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